Anti-PYCR2 antibody (STJA0006839)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PYCR2
General Information
| Short Description | Rabbit polyclonal anti-Pyrroline-5-carboxylate reductase 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PYCR2 |
| Gene ID | 29920 |
| Uniprot ID | P5CR2_HUMAN |
| Immunogen | Synthesized peptide derived from human PYCR2 |
| Specificity | This antibody detects endogenous levels of PYCR2 at Human, Mouse, Rat |
Additional Info
| Function | Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in cellular response to oxidative stress. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). |
| Protein Name | Pyrroline-5-Carboxylate Reductase 2P5c Reductase 2P5cr 2 |
| Database Links | Reactome: R-HSA-8964539 |
| Cellular Localisation | CytoplasmMitochondrion |
| Alternative Antibody Names | Anti-Pyrroline-5-Carboxylate Reductase 2 antibodyAnti-P5c Reductase 2 antibodyAnti-P5cr 2 antibodyAnti-PYCR2 antibody |
Information sourced from Uniprot.org