Anti-PYCR1 antibody [SRM14983] (STJ11109713)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal PYCR1 antibody for use in WB, IF, ICC, IF-P, IHC-P and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/IF-P/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM14983 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB, 1:12000-1:72000IF/ICC, 1:200-1:2000IF-P, 1:200-1:2000IHC-P, 1:200-1:800ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PYCR1 |
| Gene ID | 5831 |
| Uniprot ID | P5CR1_HUMAN |
| Immunogen | Synthetic peptide. This information is considered to be commercially sensitive. |
Additional Info
| Function | Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in the cellular response to oxidative stress. |
| Protein Name | Pyrroline-5-Carboxylate Reductase 1 - MitochondrialP5c Reductase 1P5cr 1 |
| Database Links | Reactome: R-HSA-8964539 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Pyrroline-5-Carboxylate Reductase 1 - Mitochondrial antibodyAnti-P5c Reductase 1 antibodyAnti-P5cr 1 antibodyAnti-PYCR1 antibody |
Information sourced from Uniprot.org