| Function | Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains. |
| Protein Name | 2-Phosphoxylose Phosphatase 1Acid Phosphatase-Like Protein 2Xylosyl PhosphataseEpididymis Luminal Protein 124 |
| Database Links | |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinColocalizes To Golgi Apparatus In A B3gat3-Dependent Manner |
| Alternative Antibody Names | Anti-2-Phosphoxylose Phosphatase 1 antibodyAnti-Acid Phosphatase-Like Protein 2 antibodyAnti-Xylosyl Phosphatase antibodyAnti-Epididymis Luminal Protein 124 antibodyAnti-PXYLP1 antibodyAnti-ACPL2 antibodyAnti-HEL124 antibodyAnti-XYLP antibodyAnti-UNQ370 antibodyAnti-PRO706 antibody |
Information sourced from Uniprot.org
