Anti-PXN antibody (C-Term) (STJA0005513)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal region of human Paxillin. This peptide sequence is highly conserved in rat and mouse paxillins, and is found in all three paxillin isoforms ( Alpha, Beta, and
General Information
| Short Description | Rabbit polyclonal antibody anti-Paxillin (C-Term) is suitable for use in Western Blot research applications. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Antigen Affinity Purified |
| Dilution Range | WB 1:1000 |
| Formulation | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PXN |
| Gene ID | 5829 |
| Uniprot ID | PAXI_HUMAN |
| Immunogen | A synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal region of human Paxillin. This peptide sequence is highly conserved in rat and mouse paxillins, and is found in all three paxillin isoforms ( Alpha, Beta, and |
| Immunogen Region | C-Term |
| Specificity | This antibody detects a 68kDa* protein corresponding to the molecular mass of paxillin on SDS-PAGE immunoblots of A431 cells. |
Additional Info
| Function | Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Recruits other proteins such as TRIM15 to focal adhesion. |
| Protein Name | Paxillin |
| Database Links | Reactome: R-HSA-180292Reactome: R-HSA-4420097Reactome: R-HSA-445355Reactome: R-HSA-446343Reactome: R-HSA-446388Reactome: R-HSA-8849471 |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionFocal AdhesionCell CortexColocalizes With Integrins At The Cell PeripheryColocalize With Pxn To Membrane Ruffles And The Leading Edge Of Migrating Cells |
| Alternative Antibody Names | Anti-Paxillin antibodyAnti-PXN antibody |
Information sourced from Uniprot.org