| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Paxillin (144-193 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PXN |
| Gene ID: | 5829 |
| Uniprot ID: | PAXI_HUMAN |
| Immunogen Region: | 144-193 aa |
| Specificity: | Paxillin Polyclonal Antibody detects endogenous levels of Paxillin protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human Paxillin at the amino acid range 144-193 |
| Function | Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Recruits other proteins such as TRIM15 to focal adhesion. |
| Protein Name | Paxillin |
| Database Links | Reactome: R-HSA-180292 Reactome: R-HSA-4420097 Reactome: R-HSA-445355 Reactome: R-HSA-446343 Reactome: R-HSA-446388 Reactome: R-HSA-8849471 |
| Cellular Localisation | Cytoplasm Cytoskeleton Cell Junction Focal Adhesion Cell Cortex Colocalizes With Integrins At The Cell Periphery Colocalize With Pxn To Membrane Ruffles And The Leading Edge Of Migrating Cells |
| Alternative Antibody Names | Anti-Paxillin antibody Anti-PXN antibody |
Information sourced from Uniprot.org