Anti-Pulmonary Surfactant Associated Protein D antibody [R06-2B1] (STJA0034900)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of mouse Surfactant protein D
General Information
| Short Description | Rabbit monoclonal anti-Pulmonary Surfactant Associated Protein D for use in WB and IHC-P in Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-2B1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | Sftpd |
| Gene ID | 20390 |
| Uniprot ID | SFTPD_MOUSE |
| Immunogen | Recombinant protein of mouse Surfactant protein D |
Additional Info
| Post Translational Modifications | S-nitrosylation at Cys-34 and Cys-39 alters the quaternary structure which results in a pro-inflammatory chemoattractive signaling activity with macrophages. |
| Function | Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. |
| Protein Name | Pulmonary Surfactant-Associated Protein DPsp-DSp-DLung Surfactant Protein D |
| Database Links | Reactome: R-MMU-166016Reactome: -MMU-198933Reactome: -MMU-391160Reactome: -MMU-5683826Reactome: -MMU-5686938 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixSurface Film |
| Alternative Antibody Names | Anti-Pulmonary Surfactant-Associated Protein D antibodyAnti-Psp-D antibodyAnti-Sp-D antibodyAnti-Lung Surfactant Protein D antibodyAnti-Sftpd antibodyAnti-Sftp4 antibody |
Information sourced from Uniprot.org