| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PTS |
| Gene ID: | 5805 |
| Uniprot ID: | PTPS_HUMAN |
| Immunogen Region: | 1-145 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human PTS (NP_000308.1). |
| Immunogen Sequence: | MSTEGGGRRCQAQVSRRISF SASHRLYSKFLSDEENLKLF GKCNNPNGHGHNYKVVVTVH GEIDPATGMVMNLADLKKYM EEAIMQPLDHKNLDMDVPYF ADVVSTTENVAVYIWDNLQK VLPVGVLYKVKVYETDNNIV VYKGE |
| Post Translational Modifications | Phosphorylation of Ser-19 is required for maximal enzyme activity. |
| Function | Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin. |
| Protein Name | 6-Pyruvoyl Tetrahydrobiopterin SynthasePtp SynthasePtps |
| Database Links | Reactome: R-HSA-1474151 |
| Alternative Antibody Names | Anti-6-Pyruvoyl Tetrahydrobiopterin Synthase antibodyAnti-Ptp Synthase antibodyAnti-Ptps antibodyAnti-PTS antibody |
Information sourced from Uniprot.org
