Anti-PTP4A2 antibody [R02-1H6] (STJA0035338)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human PTP4A2/PRL2
General Information
| Short Description | Rabbit monoclonal anti-PTP4A2 for use in WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-1H6 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PTP4A2 |
| Gene ID | 8073 |
| Uniprot ID | TP4A2_HUMAN |
| Immunogen | A synthetic peptide of human PTP4A2/PRL2 |
Additional Info
| Tissue Specificity | Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue. |
| Post Translational Modifications | Farnesylated. Farnesylation is required for membrane targeting and for interaction with RABGGTB. Unfarnesylated forms are redirected to the nucleus and cytosol. |
| Function | Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB. |
| Protein Name | Protein Tyrosine Phosphatase Type Iva 2Hu-Pp-1Ov-1Ptp(CaaxiiProtein-Tyrosine Phosphatase 4a2Protein-Tyrosine Phosphatase Of Regenerating Liver 2Prl-2 |
| Database Links | Reactome: R-HSA-8873719 |
| Cellular Localisation | Cell MembraneEarly EndosomeCytoplasm |
| Alternative Antibody Names | Anti-Protein Tyrosine Phosphatase Type Iva 2 antibodyAnti-Hu-Pp-1 antibodyAnti-Ov-1 antibodyAnti-Ptp(Caaxii antibodyAnti-Protein-Tyrosine Phosphatase 4a2 antibodyAnti-Protein-Tyrosine Phosphatase Of Regenerating Liver 2 antibodyAnti-Prl-2 antibodyAnti-PTP4A2 antibodyAnti-PRL2 antibodyAnti-PTPCAAX2 antibodyAnti-BM-008 antibody |
Information sourced from Uniprot.org