| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PTH2R |
| Gene ID: | 5746 |
| Uniprot ID: | PTH2R_HUMAN |
| Immunogen Region: | 27-145 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-145 of human PTH2R (NP_005039.1). |
| Immunogen Sequence: | DSDGTITIEEQIVLVLKAKV QCELNITAQLQEGEGNCFPE WDGLICWPRGTVGKISAVPC PPYIYDFNHKGVAFRHCNPN GTWDFMHSLNKTWANYSDCL RFLQPDISIGKQEFFERLY |
| Tissue Specificity | Expressed abundantly in brain and pancreas. Also expressed in the testis. |
| Function | This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor. |
| Protein Name | Parathyroid Hormone 2 ReceptorPth2 Receptor |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Parathyroid Hormone 2 Receptor antibodyAnti-Pth2 Receptor antibodyAnti-PTH2R antibodyAnti-PTHR2 antibody |
Information sourced from Uniprot.org