| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PTH2R (27-145) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PTH2R |
| Gene ID: |
5746 |
| Uniprot ID: |
PTH2R_HUMAN |
| Immunogen Region: |
27-145 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 27-145 of human PTH2R (NP_005039.1). |
| Immunogen Sequence: |
DSDGTITIEEQIVLVLKAKV QCELNITAQLQEGEGNCFPE WDGLICWPRGTVGKISAVPC PPYIYDFNHKGVAFRHCNPN GTWDFMHSLNKTWANYSDCL RFLQPDISIGKQEFFERLY |
| Tissue Specificity | Expressed abundantly in brain and pancreas. Also expressed in the testis. |
| Function | This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor. |
| Protein Name | Parathyroid Hormone 2 ReceptorPth2 Receptor |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Parathyroid Hormone 2 Receptor antibodyAnti-Pth2 Receptor antibodyAnti-PTH2R antibodyAnti-PTHR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
