Anti-BAALC antibody (1-145) (STJ117708)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal BAALC (1-145) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BAALC |
| Gene ID | 79870 |
| Uniprot ID | BAALC_HUMAN |
| Immunogen Region | 1-145 |
| Immunogen Sequence | MGCGGSRADAIEPRYYESWT RETESTWLTYTDSDAPPSAA APDSGPEAGGLHSGMLEDGL PSNGVPRSTAPGGIPNPEKK TNCETQCPNPQSLSSGPLTQ KQNGLQTTEAKRDAKRMPAK EVTINVTDSIQQMDRSRRIT KNCVN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human BAALC (NP_079088.1). |
Additional Info
| Tissue Specificity | Predominantly expressed in neuroectoderm-derived tissues. Expressed in the brain and spinal cord, and at low levels, in the adrenal gland. In the bone marrow, confined to the CD34+ progenitor cells. Not found in peripheral blood mononuclear cells, nor lymph nodes. Tends to be expressed at high levels in acute myeloid leukemia and glioblastoma cells. |
| Post Translational Modifications | Palmitoylation and myristoylation target the protein to the lipid rafts. |
| Function | May play a synaptic role at the postsynaptic lipid rafts possibly through interaction with CAMK2A. |
| Protein Name | Brain And Acute Leukemia Cytoplasmic Protein |
| Database Links | |
| Cellular Localisation | CytoplasmSynapseSynaptosomeMembrane RaftPostsynaptic DensityIn NeuronsLocalizes To Postsynaptic Lipid RaftsIn Myocardial And Skeletal Muscle CellsLocalizes To The Cytoplasm Adjacent To The Inner Cell MembranePolarized To One End Of The Myocyte |
| Alternative Antibody Names | Anti-Brain And Acute Leukemia Cytoplasmic Protein antibodyAnti-BAALC antibody |
Information sourced from Uniprot.org