• Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-PTGIS antibody (C-Term) (STJ95055)

SKU:
STJ95055

€60.00 - €315.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Prostacyclin synthase (C-Term) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTGIS
Gene ID: 5740
Uniprot ID: PTGIS_HUMAN
Immunogen Region: C-Term
Specificity: PGI2 synthase Polyclonal Antibody detects endogenous levels of PGI2 synthase protein.
Immunogen: Synthesized peptide derived from the C-terminal region of human PGI2 synthase.
Function Catalyzes the biosynthesis and metabolism of eicosanoids. Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2), a potent mediator of vasodilation and inhibitor of platelet aggregation. Additionally, displays dehydratase activity, toward hydroperoxyeicosatetraenoates (HPETEs), especially toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE).
Protein Name Prostacyclin Synthase
Hydroperoxy Icosatetraenoate Dehydratase
Prostaglandin I2 Synthase
Database Links Reactome: R-HSA-197264
Reactome: R-HSA-211979
Reactome: R-HSA-2162123
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Prostacyclin Synthase antibody
Anti-Hydroperoxy Icosatetraenoate Dehydratase antibody
Anti-Prostaglandin I2 Synthase antibody
Anti-PTGIS antibody
Anti-CYP8 antibody
Anti-CYP8A1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance