• Immunohistochemistry analysis of paraffin-embedded human stomach using PTGIR antibody (STJ25203) at dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human gastric cancer using PTGIR antibody (STJ25203) at dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of extracts of various cell lines, using PTGIR antibody (STJ25203) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-PTGIR antibody (207-386) (STJ25203)

SKU:
STJ25203

£169.50 - £449.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PTGIR (207-386) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTGIR
Gene ID: 5739
Uniprot ID: PI2R_HUMAN
Immunogen Region: 207-386
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 207-386 of human PTGIR (NP_000951.1).
Immunogen Sequence: TLSLCRMYRQQKRHQGSLGP RPRTGEDEVDHLILLALMTV VMAVCSLPLTIRCFTQAVAP DSSSEMGDLLAFRFYAFNPI LDPWVFILFRKAVFQRLKLW VCCLCLGPAHGDSQTPLSQL ASGRRDPRAPSAPVGKEGSC VPLSAWGEGQVEPLPPTQQS SGSAVGTSSKAEASVACSLC
Post Translational Modifications Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C.
Function Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
Protein Name Prostacyclin Receptor
Prostaglandin I2 Receptor
Pgi Receptor
Pgi2 Receptor
Prostanoid Ip Receptor
Database Links Reactome: R-HSA-391908
Reactome: R-HSA-392851
Reactome: R-HSA-418555
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Prostacyclin Receptor antibody
Anti-Prostaglandin I2 Receptor antibody
Anti-Pgi Receptor antibody
Anti-Pgi2 Receptor antibody
Anti-Prostanoid Ip Receptor antibody
Anti-PTGIR antibody
Anti-PRIPR antibody

Information sourced from Uniprot.org

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