Anti-PTGFR antibody (C-Term) (STJ73224)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-PTGFR (C-Term) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:1000.WB: Not yet tested. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the a |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | PTGFR |
| Gene ID | 5737 |
| Uniprot ID | PF2R_HUMAN |
| Accession Number | NP_000950.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | ESPVAEKSAST |
| Specificity | This antibody is expected to recognize isoform a (NP_000950.1) only. |
Additional Info
| Function | Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum. Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes.heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost. |
| Protein Name | Prostaglandin F2-Alpha ReceptorPgf ReceptorPgf2-Alpha ReceptorProstanoid Fp Receptor |
| Database Links | Reactome: R-HSA-391908Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Prostaglandin F2-Alpha Receptor antibodyAnti-Pgf Receptor antibodyAnti-Pgf2-Alpha Receptor antibodyAnti-Prostanoid Fp Receptor antibodyAnti-PTGFR antibody |
Information sourced from Uniprot.org