• STJ71343 (3ug/ml) staining of Mouse Testes (A) lysate and nuclear NIH3T3 (B) cell lysate (35µg protein in RIPA buffer). Detected by chemiluminescence.
  • STJ71343 Immunofluorescence analysis of paraformaldehyde fixed A431 cells, permeabilized with 0. 15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml) , showing nuclear staining. Actin filaments were stained with phalloidin (red) and the nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).

Anti-PTBP2 antibody (Internal) (STJ71343)

SKU:
STJ71343-100

$409.73
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Host: Goat
Applications: Pep-ELISA/WB/IF
Reactivity: Human/Mouse/Rat/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-PTBP2 (Internal) is suitable for use in ELISA, Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IF-Strong expression of the protein seen in the nuclei of A431 cells. 10µg/ml
ELISA-antibody detection limit dilution 1:1000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: PTBP2
Gene ID: 58155
Uniprot ID: PTBP2_HUMAN
Immunogen Region: Internal
Accession Number: NP_001287914.1; NP_001287915.1; NP_001287916.1; NP_001287917.1; NP_001287918.1; NP_067013.1 ;
Specificity: This antibody is expected to recognise NP_001287914.1 (isoform 1) , NP_001287915.1 (isoform 2) , NP_001287916.1 (isoform 3) , NP_001287917.1 (isoform 4) , NP_001287918.1 (isoform 5) , and NP_067013.1 (isoform 6).
Immunogen Sequence: SKKFKGEDKMD
Function RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5: Reduced affinity for RNA.
Protein Name Polypyrimidine Tract-Binding Protein 2
Neural Polypyrimidine Tract-Binding Protein
Neurally-Enriched Homolog Of Ptb
Ptb-Like Protein
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Polypyrimidine Tract-Binding Protein 2 antibody
Anti-Neural Polypyrimidine Tract-Binding Protein antibody
Anti-Neurally-Enriched Homolog Of Ptb antibody
Anti-Ptb-Like Protein antibody
Anti-PTBP2 antibody
Anti-NPTB antibody
Anti-PTB antibody
Anti-PTBLP antibody

Information sourced from Uniprot.org

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