| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PSME2 |
| Gene ID: | 5721 |
| Uniprot ID: | PSME2_HUMAN |
| Immunogen Region: | 1-239 |
| Immunogen Sequence: | MAKPCGVRLSGEARKQVEVF RQNLFQEAEEFLYRFLPQKI IYLNQLLQEDSLNVADLTSL RAPLDIPIPDPPPKDDEMET DKQEKKEVHKCGFLPGNEKV LSLLALVKPEVWTLKEKCIL VITWIQHLIPKIEDGNDFGV AIQEKVLERVNAVKTKVEAF QTTISKYFSERGDAVAKASK ETHVMDYRALVHERDEAAYG ELRAMVLDLRAFYAELYHII SSNLEKIVNPKGEEKPSMY |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-239 of human PSME2 (NP_002809.2). |
| Function | Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome. |
| Protein Name | Proteasome Activator Complex Subunit 211s Regulator Complex Subunit BetaReg-BetaActivator Of Multicatalytic Protease Subunit 2Proteasome Activator 28 Subunit BetaPa28bPa28beta |
| Database Links | Reactome: R-HSA-8950505Reactome: R-HSA-9907900 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Proteasome Activator Complex Subunit 2 antibodyAnti-11s Regulator Complex Subunit Beta antibodyAnti-Reg-Beta antibodyAnti-Activator Of Multicatalytic Protease Subunit 2 antibodyAnti-Proteasome Activator 28 Subunit Beta antibodyAnti-Pa28b antibodyAnti-Pa28beta antibodyAnti-PSME2 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and PSME2 knockout (KO) 293T cells, using [KO Validated] PSME2 Rabbit polyclonal antibody (STJ11100740) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89678/358171/STJ11100740_1__90162.1713122477.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and PSME2 knockout (KO) 293T cells, using [KO Validated] PSME2 Rabbit polyclonal antibody (STJ11100740) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
