| Short Description : | Rabbit polyclonal PSME1 (1-249) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PSME1 |
| Gene ID: | 5720 |
| Uniprot ID: | PSME1_HUMAN |
| Immunogen Region: | 1-249 |
| Immunogen Sequence: | MAMLRVQPEAQAKVDVFRED LCTKTENLLGSYFPKKISEL DAFLKEPALNEANLSNLKAP LDIPVPDPVKEKEKEERKKQ QEKEDKDEKKKGEDEDKGPP CGPVNCNEKIVVLLQRLKPE IKDVIEQLNLVTTWLQLQIP RIEDGNNFGVAVQEKVFELM TSLHTKLEGFHTQISKYFSE RGDAVTKAAKQPHVGDYRQL VHELDEAEYRDIRLMVMEIR NAYAVLYDIILKNFEKLKK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-249 of human PSME1 (NP_006254.1). |
| Function | Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome. |
| Protein Name | Proteasome Activator Complex Subunit 111s Regulator Complex Subunit AlphaReg-AlphaActivator Of Multicatalytic Protease Subunit 1Interferon Gamma Up-Regulated I-5111 ProteinIgup I-5111Proteasome Activator 28 Subunit AlphaPa28aPa28alpha |
| Database Links | Reactome: R-HSA-9907900 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Proteasome Activator Complex Subunit 1 antibodyAnti-11s Regulator Complex Subunit Alpha antibodyAnti-Reg-Alpha antibodyAnti-Activator Of Multicatalytic Protease Subunit 1 antibodyAnti-Interferon Gamma Up-Regulated I-5111 Protein antibodyAnti-Igup I-5111 antibodyAnti-Proteasome Activator 28 Subunit Alpha antibodyAnti-Pa28a antibodyAnti-Pa28alpha antibodyAnti-PSME1 antibodyAnti-IFI5111 antibody |
Information sourced from Uniprot.org
