Anti-PSMC4 antibody (1-165 aa) [SRM5381] (STJ11107292)

Name: Anti-PSMC4 antibody (1-165 aa) [SRM5381] (STJ11107292)
SKU: STJ11107292
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11107292

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General Information

Short Description	Rabbit monoclonal PSMC4 (1-165 aa) antibody for use in IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	IHC-P/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Clonality	Monoclonal
Clone ID	SRM5381
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	IHC-P:1:200-1:800 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.

Target Information

Gene Symbol	PSMC4
Gene ID	5704
Uniprot ID	PRS6B_HUMAN
Immunogen Region	1-165 aa
Immunogen Sequence	MEEIGILVEKAQDEIPALSV SRPQTGLSFLGPEPEDLEDL YSRYKKLQQELEFLEVQEEY IKDEQKNLKKEFLHAQEEVK RIQSIPLVIGQFLEAVDQNT AIVGSTTGSNYYVRILSTID RELLKPNASVALHKHSNALV DVLPPEADSSIMMLTSDQKP DVMYA
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human PSMC4 (NP_006494.1).

Additional Info

Function	Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
Protein Name	26s Proteasome Regulatory Subunit 6b 26s Proteasome Aaa-Atpase Subunit Rpt3 Mb67-Interacting Protein Mip224 Proteasome 26s Subunit Atpase 4 Tat-Binding Protein 7 Tbp-7
Database Links	Reactome: R-HSA-1169091 Reactome: R-HSA-1234176 Reactome: R-HSA-1236974 Reactome: R-HSA-1236978 Reactome: R-HSA-174084 Reactome: R-HSA-174113 Reactome: R-HSA-174154 Reactome: R-HSA-174178 Reactome: R-HSA-174184 Reactome: R-HSA-180534 Reactome: R-HSA-180585 Reactome: R-HSA-187577 Reactome: R-HSA-195253 Reactome: R-HSA-202424 Reactome: R-HSA-211733 Reactome: R-HSA-2467813 Reactome: R-HSA-2871837 Reactome: R-HSA-349425 Reactome: R-HSA-350562 Reactome: R-HSA-382556 Reactome: R-HSA-450408 Reactome: R-HSA-4608870 Reactome: R-HSA-4641257 Reactome: R-HSA-4641258 Reactome: R-HSA-5358346 Reactome: R-HSA-5362768 Reactome: R-HSA-5607761 Reactome: R-HSA-5607764 Reactome: R-HSA-5610780 Reactome: R-HSA-5610783 Reactome: R-HSA-5610785 Reactome: R-HSA-5632684 Reactome: R-HSA-5658442 Reactome: R-HSA-5668541 Reactome: R-HSA-5676590 Reactome: R-HSA-5678895 Reactome: R-HSA-5687128 Reactome: R-HSA-5689603 Reactome: R-HSA-5689880 Reactome: R-HSA-68867 Reactome: R-HSA-68949 Reactome: R-HSA-69017 Reactome: R-HSA-69481 Reactome: R-HSA-69601 Reactome: R-HSA-75815 Reactome: R-HSA-8852276 Reactome: R-HSA-8854050 Reactome: R-HSA-8939236 Reactome: R-HSA-8939902 Reactome: R-HSA-8941858 Reactome: R-HSA-8948751 Reactome: R-HSA-8951664 Reactome: R-HSA-9010553 Reactome: R-HSA-9020702 Reactome: R-HSA-9604323 Reactome: R-HSA-9755511 Reactome: R-HSA-9762114 Reactome: R-HSA-9824272 Reactome: R-HSA-983168 Reactome: R-HSA-9907900
Cellular Localisation	Cytoplasm Nucleus
Alternative Antibody Names	Anti-26s Proteasome Regulatory Subunit 6b antibody Anti-26s Proteasome Aaa-Atpase Subunit Rpt3 antibody Anti-Mb67-Interacting Protein antibody Anti-Mip224 antibody Anti-Proteasome 26s Subunit Atpase 4 antibody Anti-Tat-Binding Protein 7 antibody Anti-Tbp-7 antibody Anti-PSMC4 antibody Anti-MIP224 antibody Anti-TBP7 antibody

Information sourced from Uniprot.org

Citations

View product citations for antibody STJ11107292 on CiteAb