![Anti-PSMA antibody [SM5056] (STJA0005056)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/180113/403384/STJA0005056_1__07034.1738950447.png?c=1 "Anti-PSMA antibody [SM5056] (STJA0005056)")
![Anti-PSMA antibody [SM5056] (STJA0005056)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/180113/403384/STJA0005056_1__07034.1738950447.png?c=1 "Anti-PSMA antibody [SM5056] (STJA0005056)")
Anti-PSMA antibody [SM5056] (STJA0005056)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
ImmunogenSynthesized peptide derived from human Prostate-Specific Membrane Antigen (PSMA)
General Information
| Short Description | Mouse monoclonal anti-PSMA for use in IHC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SM5056 |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | IHC/IF (H) 1:200-1:500 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage Instruction | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Target Information
| Gene Symbol | FOLH1 |
| Gene ID | 2346 |
| Uniprot ID | FOLH1_HUMAN |
| Immunogen | Synthesized peptide derived from human Prostate-Specific Membrane Antigen (PSMA) |
Additional Info
| Post Translational Modifications | The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis. The N-terminus is blocked. |
| Function | Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC. |
| Protein Name | Glutamate Carboxypeptidase 2Cell Growth-Inhibiting Gene 27 ProteinFolate Hydrolase 1Folylpoly-Gamma-Glutamate CarboxypeptidaseFgcpGlutamate Carboxypeptidase IiGcpiiMembrane Glutamate CarboxypeptidaseMgcpN-Acetylated-Alpha-Linked Acidic Dipeptidase INaaladase IProstate-Specific Membrane AntigenPsmPsmaPteroylpoly-Gamma-Glutamate Carboxypeptidase |
| Database Links | Reactome: R-HSA-8963693 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinIsoform Psma': Cytoplasm |
| Alternative Antibody Names | Anti-Glutamate Carboxypeptidase 2 antibodyAnti-Cell Growth-Inhibiting Gene 27 Protein antibodyAnti-Folate Hydrolase 1 antibodyAnti-Folylpoly-Gamma-Glutamate Carboxypeptidase antibodyAnti-Fgcp antibodyAnti-Glutamate Carboxypeptidase Ii antibodyAnti-Gcpii antibodyAnti-Membrane Glutamate Carboxypeptidase antibodyAnti-Mgcp antibodyAnti-N-Acetylated-Alpha-Linked Acidic Dipeptidase I antibodyAnti-Naaladase I antibodyAnti-Prostate-Specific Membrane Antigen antibodyAnti-Psm antibodyAnti-Psma antibodyAnti-Pteroylpoly-Gamma-Glutamate Carboxypeptidase antibodyAnti-FOLH1 antibodyAnti-FOLH antibodyAnti-NAALAD1 antibodyAnti-PSM antibodyAnti-PSMA antibodyAnti-GIG27 antibody |
Information sourced from Uniprot.org