| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PH and SEC7 domain-containing protein 4 is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PSD4 |
| Gene ID: |
23550 |
| Uniprot ID: |
PSD4_HUMAN |
| Specificity: |
PSD4 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Function | Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate. |
| Protein Name | Ph And Sec7 Domain-Containing Protein 4Exchange Factor For Adp-Ribosylation Factor Guanine Nucleotide Factor 6 BExchange Factor For Arf6 BPleckstrin Homology And Sec7 Domain-Containing Protein 4Telomeric Of Interleukin-1 Cluster Protein |
| Cellular Localisation | Cell MembraneCell ProjectionRuffle MembraneIn Interphase Associated With The Plasma MembraneIn Particular With Membrane Ruffling RegionsAccumulates In Dynamic Actin-Rich Membrane Ruffles And Microvilli-Like StructuresRecruited To Membranes Via Phosphatidylinositol Phosphate-Binding (Probable) |
| Alternative Antibody Names | Anti-Ph And Sec7 Domain-Containing Protein 4 antibodyAnti-Exchange Factor For Adp-Ribosylation Factor Guanine Nucleotide Factor 6 B antibodyAnti-Exchange Factor For Arf6 B antibodyAnti-Pleckstrin Homology And Sec7 Domain-Containing Protein 4 antibodyAnti-Telomeric Of Interleukin-1 Cluster Protein antibodyAnti-PSD4 antibodyAnti-EFA6B antibodyAnti-TIC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
