Anti-PSAT1 antibody (1-370) (STJ116059)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PSAT1 (1-370) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PSAT1 |
| Gene ID | 29968 |
| Uniprot ID | SERC_HUMAN |
| Immunogen Region | 1-370 |
| Immunogen Sequence | MDAPRQVVNFGPGPAKLPHS VLLEIQKELLDYKGVGISVL EMSHRSSDFAKIINNTENLV RELLAVPDNYKVIFLQGGGC GQFSAVPLNLIGLKAGRCAD YVVTGAWSAKAAEEAKKFGT INIVHPKLGSYTKIPDPSTW NLNPDASYVYYCANETVHGV EFDFIPDVKGAVLVCDMSSN FLSKPVDVSKFGVIFAGAQK NVGSAGVTVVIVRDDLLGFA LRECPSVLEYKVQAGNSSL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-370 of human PSAT1 (NP_478059.1). |
Additional Info
| Tissue Specificity | Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon. |
| Function | Involved in L-serine biosynthesis via the phosphorylated pathway, a three-step pathway converting the glycolytic intermediate 3-phospho-D-glycerate into L-serine. Catalyzes the second step, that is the pyridoxal 5'-phosphate-dependent transamination of 3-phosphohydroxypyruvate and L-glutamate to O-phosphoserine (OPS) and alpha-ketoglutarate. |
| Protein Name | Phosphoserine AminotransferasePhosphohydroxythreonine AminotransferasePsat |
| Database Links | Reactome: R-HSA-977347 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Phosphoserine Aminotransferase antibodyAnti-Phosphohydroxythreonine Aminotransferase antibodyAnti-Psat antibodyAnti-PSAT1 antibodyAnti-PSA antibody |
Information sourced from Uniprot.org