Anti-PRUNE antibody (STJA0004552)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFull length fusion protein
General Information
| Short Description | Rabbit polyclonal anti-Exopolyphosphatase Prune1 for use in IHC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | IHC 1:30-1:150 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | PRUNE1 |
| Gene ID | 58497 |
| Uniprot ID | PRUN1_HUMAN |
| Immunogen | Full length fusion protein |
Additional Info
| Tissue Specificity | Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas. |
| Function | Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, migration and differentiation, and acts as a negative regulator of NME1. Plays a role in the regulation of neurogenesis. Involved in the regulation of microtubule polymerization. |
| Protein Name | Exopolyphosphatase Prune1Drosophila-Related Expressed Sequence 17Dres-17Dres17Htcd37Protein Prune Homolog 1Hprune |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusCell JunctionFocal AdhesionIn Some Transfected Cells A Nuclear Staining Is Also Observed |
| Alternative Antibody Names | Anti-Exopolyphosphatase Prune1 antibodyAnti-Drosophila-Related Expressed Sequence 17 antibodyAnti-Dres-17 antibodyAnti-Dres17 antibodyAnti-Htcd37 antibodyAnti-Protein Prune Homolog 1 antibodyAnti-Hprune antibodyAnti-PRUNE1 antibodyAnti-PRUNE antibody |
Information sourced from Uniprot.org