Anti-PRSS2 antibody (STJ193165)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human TRY2
General Information
| Short Description | Rabbit polyclonal anti-Trypsin-2 for use in IHC, IF and WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC-P 1:50-200WB 1:500-2000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PRSS2 |
| Gene ID | 5645 |
| Uniprot ID | TRY2_HUMAN |
| Immunogen | Synthesized peptide derived from the human TRY2 |
| Specificity | This antibody detects endogenous levels of human TRY2 |
Additional Info
| Post Translational Modifications | Sulfated on tyrosine. Sulfation at Tyr-154 increases selectivity towards basic versus apolar residues at the P2' position of inhibitors that bind in a substrate-like fashion. Although the increase in selectivity is relatively small, it may facilitate digestion of a broader range of dietary proteins. |
| Function | In the ileum, may be involved in defensin processing, including DEFA5. |
| Protein Name | Trypsin-2Anionic TrypsinogenSerine Protease 2Trypsin Ii |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1462054Reactome: R-HSA-1592389Reactome: R-HSA-6798695Reactome: R-HSA-6803157 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Antibody Names | Anti-Trypsin-2 antibodyAnti-Anionic Trypsinogen antibodyAnti-Serine Protease 2 antibodyAnti-Trypsin Ii antibodyAnti-PRSS2 antibodyAnti-TRY2 antibodyAnti-TRYP2 antibody |
Information sourced from Uniprot.org