Anti-PRSS2 antibody [R02-9K3] (STJA0037422)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human PRSS2
General Information
| Short Description | Rabbit monoclonal anti-PRSS2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-9K3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PRSS2 |
| Gene ID | 5645 |
| Uniprot ID | TRY2_HUMAN |
| Immunogen | A synthesized peptide derived from human PRSS2 |
Additional Info
| Tissue Specificity | Expressed in Paneth cells, at the base of small intestinal crypts. |
| Post Translational Modifications | Sulfated on tyrosine. Sulfation at Tyr-154 increases selectivity towards basic versus apolar residues at the P2' position of inhibitors that bind in a substrate-like fashion. Although the increase in selectivity is relatively small, it may facilitate digestion of a broader range of dietary proteins. |
| Function | In the ileum, may be involved in defensin processing, including DEFA5. |
| Protein Name | Trypsin-2Anionic TrypsinogenSerine Protease 2Trypsin Ii |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1462054Reactome: R-HSA-1592389Reactome: R-HSA-6798695Reactome: R-HSA-6803157 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Antibody Names | Anti-Trypsin-2 antibodyAnti-Anionic Trypsinogen antibodyAnti-Serine Protease 2 antibodyAnti-Trypsin Ii antibodyAnti-PRSS2 antibodyAnti-TRY2 antibodyAnti-TRYP2 antibody |
Information sourced from Uniprot.org