• Immunoflourescence of mixed fibroblasts and PC12 cells labeled with anti-peripherin (STJA0003748, green, 1:5000) and anti-vimentin (red). The blue is DAPI staining nuclear DNA. Peripherin is labeled in only the PC12 cells cytoplasmic filaments and vimentin is only labeled in the fibroblasts intermediate filaments where peripherin is not present.
  • Immunoflourescence of cultured rat neurons and glia showing peripherin (STJA0003748, green, 1:500) and alpha-internexin (red). The blue stain is nuclear DNA. Cells expressing both peripherin and alpha-internexin appear yellow.
  • Western blot of rat cerebellar lysate showing specific immunolabeling of the ~57 kDa peripherin protein.

Anti-PRPH antibody (STJA0003748)

SKU:
STJA0003748-100

£394.50
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Host: Chicken
Applications: WB/IHC/ICC
Reactivity: Bovine/Human/Mouse/Rat/Canine/Feline/Goat/Guinea Pig/Hamster/Horse/Non-Human Primates/Rabbit/Sheep
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Chicken polyclonal antibody anti-Peripherin is suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgY
Formulation: Total IgY fraction in PBS + 10 mM Sodium Azide.
Purification: This antibody was total igy fraction.
Dilution Range: WB 1:1000
IHC 1:500-1:2000
ICC 1:500-1:5000
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PrphUniprot ID=PERI_RAT"
Immunogen: Recombinant rat peripherin expressed in and purification from E. coli.
Tissue Specificity Expressed in hypoglossal motor neurons (at protein level). Expressed in the small and large sensory neurons of the dorsal root ganglion (at protein level). Expressed in cutaneous and muscular sensory neurons.
Post Translational Modifications Phosphorylated.phosphorylation increases after nerve injury in regenerating neurons.
Function Class-III neuronal intermediate filament protein. My form an independent structural network without the involvement of other neurofilaments or may cooperate with the neuronal intermediate filament proteins NEFL, NEFH, NEFM and INA to form a filamentous network. Assembly of the neuronal intermediate filaments may be regulated by RAB7A. Plays a role in the development of unmyelinated sensory neurons. May be involved in axon elongation and axon regeneration after injury. Inhibits neurite extension in type II spiral ganglion neurons in the cochlea.
Protein Name Peripherin
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Axon
Perikaryon
Alternative Antibody Names Anti-Peripherin antibody
Anti-Prph antibody
Anti-Prph1 antibody

Information sourced from Uniprot.org

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