Anti-PRPH antibody [3H1] (STJ196645)

SKU:
STJ196645

Current Stock:
Host: Mouse
Applications: WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Peripherin is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: 3H1
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PRPH
Gene ID: 5630
Uniprot ID: PERI_HUMAN
Specificity: This antibody detects endogenous levels of Peripherin at H, R
Immunogen: Synthesized peptide derived from the human Peripherin
Post Translational Modifications Phosphorylated.phosphorylation increases after nerve injury in regenerating neurons.
Function Class-III neuronal intermediate filament protein. May form an independent structural network without the involvement of other neurofilaments or may cooperate with the neuronal intermediate filament proteins NEFL, NEFH, NEFM and INA to form a filamentous network. Assembly of the neuronal intermediate filaments may be regulated by RAB7A. Plays a role in the development of unmyelinated sensory neurons. May be involved in axon elongation and axon regeneration after injury. Inhibits neurite extension in type II spiral ganglion neurons in the cochlea.
Protein Name Peripherin
Neurofilament 4
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Axon
Perikaryon
Alternative Antibody Names Anti-Peripherin antibody
Anti-Neurofilament 4 antibody
Anti-PRPH antibody
Anti-NEF4 antibody
Anti-PRPH1 antibody

Information sourced from Uniprot.org

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