Anti-PRPF31 antibody (331-380 aa) (STJ95232)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PRP31 at the amino acid range 331-380
General Information
| Short Description | Rabbit polyclonal anti-U4/U6 small nuclear ribonucleoprotein Prp31 (331-380 aa) for use in WB, ELISA and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PRPF31 |
| Gene ID | 26121 |
| Uniprot ID | PRP31_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PRP31 at the amino acid range 331-380 |
| Immunogen Region | 331-380 aa |
| Specificity | PRPF31 Polyclonal Antibody detects endogenous levels of PRPF31 protein. |
Additional Info
| Post Translational Modifications | Phosphorylated by PRP4K during spliceosome assembly. |
| Function | Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. |
| Protein Name | U4/U6 Small Nuclear Ribonucleoprotein Prp31Pre-Mrna-Processing Factor 31Serologically Defined Breast Cancer Antigen Ny-Br-99U4/U6 Snrnp 61 Kda ProteinProtein 61kHprp31 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusNucleus SpeckleCajal BodyPredominantly Found In Speckles And In Cajal Bodies |
| Alternative Antibody Names | Anti-U4/U6 Small Nuclear Ribonucleoprotein Prp31 antibodyAnti-Pre-Mrna-Processing Factor 31 antibodyAnti-Serologically Defined Breast Cancer Antigen Ny-Br-99 antibodyAnti-U4/U6 Snrnp 61 Kda Protein antibodyAnti-Protein 61k antibodyAnti-Hprp31 antibodyAnti-PRPF31 antibodyAnti-PRP31 antibody |
Information sourced from Uniprot.org