• Western blot analysis of various lysates using PROZ Rabbit polyclonal antibody (STJ118522) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-PROZ antibody (220-340) (STJ118522)

SKU:
STJ118522

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PROZ (220-340) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PROZ
Gene ID: 8858
Uniprot ID: PROZ_HUMAN
Immunogen Region: 220-340
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-340 of human PROZ (NP_003882.1).
Immunogen Sequence: SLLHRNITVKTYFNRTSQDP LMIKITHVHVHMRYDADAGE NDLSLLELEWPIQCPGAGLP VCTPEKDFAEHLLIPRTRGL LSGWARNGTDLGNSLTTRPV TLVEGEECGQVLNVTVTTRT Y
Tissue Specificity Plasma.
Post Translational Modifications The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
Function Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids.
Protein Name Vitamin K-Dependent Protein Z
Database Links Reactome: R-HSA-159740
Reactome: R-HSA-159763
Reactome: R-HSA-159782
Cellular Localisation Secreted
Alternative Antibody Names Anti-Vitamin K-Dependent Protein Z antibody
Anti-PROZ antibody

Information sourced from Uniprot.org

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