Anti-PROZ antibody (220-340) (STJ118522)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PROZ (220-340) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PROZ |
| Gene ID | 8858 |
| Uniprot ID | PROZ_HUMAN |
| Immunogen Region | 220-340 |
| Immunogen Sequence | SLLHRNITVKTYFNRTSQDP LMIKITHVHVHMRYDADAGE NDLSLLELEWPIQCPGAGLP VCTPEKDFAEHLLIPRTRGL LSGWARNGTDLGNSLTTRPV TLVEGEECGQVLNVTVTTRT Y |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 220-340 of human PROZ (NP_003882.1). |
Additional Info
| Tissue Specificity | Plasma. |
| Post Translational Modifications | The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. |
| Function | Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids. |
| Protein Name | Vitamin K-Dependent Protein Z |
| Database Links | Reactome: R-HSA-159740Reactome: R-HSA-159763Reactome: R-HSA-159782 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Vitamin K-Dependent Protein Z antibodyAnti-PROZ antibody |
Information sourced from Uniprot.org