Anti-PROX1 antibody [PT1306R] (STJA0040044)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgGk
General Information
| Short Description | Rabbit monoclonal anti-Prospero Homeobox Protein 1 for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | PT1306R |
| Isotype | IgGk |
| Conjugation | Unconjugated |
| Purification | Protein A |
| Dilution Range | IHC 1:100-1:500WB 1:2000-1:10000IF 1:200-1:1000ELISA 1:5000-1:20000 |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PROX1 |
| Gene ID | 5629 |
| Uniprot ID | PROX1_HUMAN |
| Specificity | Endogenous |
Additional Info
| Function | Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3. |
| Protein Name | Prospero Homeobox Protein 1Homeobox Prospero-Like Protein Prox1Prox-1 |
| Database Links | |
| Cellular Localisation | NucleusRorg Promotes Its Nuclear Localization |
| Alternative Antibody Names | Anti-Prospero Homeobox Protein 1 antibodyAnti-Homeobox Prospero-Like Protein Prox1 antibodyAnti-Prox-1 antibodyAnti-PROX1 antibody |
Information sourced from Uniprot.org