Anti-Proteinase Inhibitor 9 antibody [PI9-17] (STJ16100180)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
Immunogenfl recombinant PI9
STJ16100180-1
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General Information

Short DescriptionMouse monoclonal anti-Proteinase Inhibitor 9 for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC/WB
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDPI9-17
IsotypeIgG1
ConjugationUnconjugated
Concentration250 Mu g/mL
Dilution RangeIHC 1:100
WB
Formulationserumfree culture supernatant with 0.7% BSA and 0.1% sodium azide
Storage InstructionStore at 2-8°C for up to 1-year, upon receipt.

Target Information

Immunogenfl recombinant PI9

Additional Info

Background The human intracellular serpin proteinase inhibitor 9 (PI9) is the only human protein able to inhibit the activity of the serine protease granzyme B. Granzyme B is expressed by cytotoxic lymphocytes and induces rapid target cell apoptosis. PI9-17 Mab was selected after immunization with full length recombinant PI9 produced in Escherichia coli. No cross reactivity with other, homologous serpins (PI6, PI8 and PAI-2) was observed.

Information sourced from Uniprot.org

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