Anti-Proteasome beta 9 antibody [R08-1M2] (STJA0036709)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Proteasome 20S LMP2
General Information
| Short Description | Rabbit monoclonal anti-Proteasome beta 9 for use in WB, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R08-1M2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PSMB9 |
| Gene ID | 5698 |
| Uniprot ID | PSB9_HUMAN |
| Immunogen | A synthesized peptide derived from human Proteasome 20S LMP2 |
Additional Info
| Post Translational Modifications | Autocleaved. The resulting N-terminal Thr residue of the mature subunit is responsible for the nucleophile proteolytic activity. |
| Function | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. |
| Protein Name | Proteasome Subunit Beta Type-9Low Molecular Mass Protein 2Macropain Chain 7Multicatalytic Endopeptidase Complex Chain 7Proteasome Chain 7Proteasome Subunit Beta-1iReally Interesting New Gene 12 Protein |
| Database Links | Reactome: R-HSA-9907900 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Proteasome Subunit Beta Type-9 antibodyAnti-Low Molecular Mass Protein 2 antibodyAnti-Macropain Chain 7 antibodyAnti-Multicatalytic Endopeptidase Complex Chain 7 antibodyAnti-Proteasome Chain 7 antibodyAnti-Proteasome Subunit Beta-1i antibodyAnti-Really Interesting New Gene 12 Protein antibodyAnti-PSMB9 antibodyAnti-LMP2 antibodyAnti-PSMB6i antibodyAnti-RING12 antibody |
Information sourced from Uniprot.org