• Immunofluorescence analysis of human placenta cells using PROK1 Rabbit monoclonal antibody (STJ11102999) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of rat placenta cells using PROK1 Rabbit monoclonal antibody (STJ11102999) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of various cell lines, using PROK1 antibody (STJ11102999) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-PROK1 antibody (1-105) [S9MR] (STJ11102999)

SKU:
STJ11102999

£146.50 - £639.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-PROK1 (1-105) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: S9MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PROK1
Gene ID: 84432
Uniprot ID: PROK1_HUMAN
Immunogen Region: 1-105
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human PROK1 (P58294).
Immunogen Sequence: MRGATRVSIMLLLVTVSDCA VITGACERDVQCGAGTCCAI SLWLRGLRMCTPLGREGEEC HPGSHKVPFFRKRKHHTCPC LPNLLCSRFPDGRYRCSMDL KNINF
Tissue Specificity Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta.
Function Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.
Protein Name Prokineticin-1
Endocrine-Gland-Derived Vascular Endothelial Growth Factor
Eg-Vegf
Mambakine
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Cellular Localisation Secreted
Alternative Antibody Names Anti-Prokineticin-1 antibody
Anti-Endocrine-Gland-Derived Vascular Endothelial Growth Factor antibody
Anti-Eg-Vegf antibody
Anti-Mambakine antibody
Anti-PROK1 antibody
Anti-UNQ600 antibody
Anti-PRO1186 antibody

Information sourced from Uniprot.org

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