Anti-PROCR antibody [ZN200] (STJA0033370)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenHuman recombinant protein fragment of human PROCR (NP_006395) produced in HEK293T cell.
General Information
| Short Description | Mouse monoclonal anti-PROCR for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZN200 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 0.5-1.0 mg/mL |
| Purification | Affinity Chromatography |
| Dilution Range | IHC 1:50-1:100 |
| Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PROCR |
| Gene ID | 10544 |
| Uniprot ID | EPCR_HUMAN |
| Immunogen | Human recombinant protein fragment of human PROCR (NP_006395) produced in HEK293T cell. |
Additional Info
| Tissue Specificity | Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney. |
| Post Translational Modifications | N-glycosylated. A soluble form exists.probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form. |
| Function | Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex.plays a role in the protein C pathway controlling blood coagulation. |
| Protein Name | Endothelial Protein C ReceptorActivated Protein C ReceptorApc ReceptorEndothelial Cell Protein C ReceptorCd Antigen Cd201 |
| Database Links | Reactome: R-HSA-140875Reactome: R-HSA-202733 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Endothelial Protein C Receptor antibodyAnti-Activated Protein C Receptor antibodyAnti-Apc Receptor antibodyAnti-Endothelial Cell Protein C Receptor antibodyAnti-Cd Antigen Cd201 antibodyAnti-PROCR antibodyAnti-EPCR antibody |
Information sourced from Uniprot.org