| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PRMT8 |
| Gene ID: | 56341 |
| Uniprot ID: | ANM8_HUMAN |
| Immunogen Region: | 200-380 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-380 of human PRMT8 (NP_062828.3). |
| Immunogen Sequence: | VIFARDKWLKPGGLMFPDRA ALYVVAIEDRQYKDFKIHWW ENVYGFDMTCIRDVAMKEPL VDIVDPKQVVTNACLIKEVD IYTVKTEELSFTSAFCLQIQ RNDYVHALVTYFNIEFTKCH KKMGFSTAPDAPYTHWKQTV FYLEDYLTVRRGEEIYGTIS MKPNAKNVRDLDFTVDLDFK G |
| Tissue Specificity | Brain-specific. |
| Function | S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer. Able to mono- and dimethylate EWS protein.however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS. |
| Protein Name | Protein Arginine N-Methyltransferase 8Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-Like Protein 4 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic Side |
| Alternative Antibody Names | Anti-Protein Arginine N-Methyltransferase 8 antibodyAnti-Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-Like Protein 4 antibodyAnti-PRMT8 antibodyAnti-HRMT1L3 antibodyAnti-HRMT1L4 antibody |
Information sourced from Uniprot.org