| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Protein Arginine N-Methyltransferase 8 (200-380) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PRMT8 |
| Gene ID: |
56341 |
| Uniprot ID: |
ANM8_HUMAN |
| Immunogen Region: |
200-380 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 200-380 of human PRMT8 (NP_062828.3). |
| Immunogen Sequence: |
VIFARDKWLKPGGLMFPDRA ALYVVAIEDRQYKDFKIHWW ENVYGFDMTCIRDVAMKEPL VDIVDPKQVVTNACLIKEVD IYTVKTEELSFTSAFCLQIQ RNDYVHALVTYFNIEFTKCH KKMGFSTAPDAPYTHWKQTV FYLEDYLTVRRGEEIYGTIS MKPNAKNVRDLDFTVDLDFK G |
| Tissue Specificity | Brain-specific. |
| Function | S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer. Able to mono- and dimethylate EWS protein.however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS. |
| Protein Name | Protein Arginine N-Methyltransferase 8Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-Like Protein 4 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic Side |
| Alternative Antibody Names | Anti-Protein Arginine N-Methyltransferase 8 antibodyAnti-Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-Like Protein 4 antibodyAnti-PRMT8 antibodyAnti-HRMT1L3 antibodyAnti-HRMT1L4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and PRMT8 knockout (KO) 293T cells, using [KO Validated] PRMT8 Rabbit polyclonal antibody (STJ11100394) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89456/357967/STJ11100394_1__99373.1713122215.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and PRMT8 knockout (KO) 293T cells, using [KO Validated] PRMT8 Rabbit polyclonal antibody (STJ11100394) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
