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Anti-PRMT2 antibody (Internal) (STJ72813)

STJ72813 (2µg/ml) staining of HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
STJ72813 (2µg/ml) staining of Mouse (A) and Rat (B) Brain lysates (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
STJ72813 (2µg/ml) staining of Pig Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-PRMT2 antibody (Internal) (STJ72813)

SKU:

STJ72813-100

£303.50

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General Information
Product Properties
Target Information
Additional Info
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Host:	Goat
Applications:	Pep-ELISA/WB
Reactivity:	Human/Mouse/Rat/Pig/Cow
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-PRMT2 (Internal) is suitable for use in ELISA and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	ELISA-antibody detection limit dilution 1:64000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	PRMT2
Gene ID:	3275
Uniprot ID:	ANM2_HUMAN
Immunogen Region:	Internal
Accession Number:	NP_001526.2; NP_001229793.1; NP_001229794.1; NP_001229795.1
Specificity:	This antibody is expected to recognize all reported isoforms (NP_001526.2; NP_001229793.1; NP_001229794.1; NP_001229795.1). Reported variants represent identical protein: NP_001526.2, NP_996845.1
Immunogen Sequence:	DQPRTTKYHSVILQ

Function	Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation.
Protein Name	Protein Arginine N-Methyltransferase 2 Histone-Arginine N-Methyltransferase Prmt2
Cellular Localisation	Isoform 1: Cytoplasm Nucleus Translocates From The Cytoplasm To The Nucleus After Hormone Exposure Excluded From Nucleolus Isoform Prmt2alpha: Nucleus Isoform Prmt2beta: Cytoplasm Nucleolus Isoform Prmt2gamma: Nucleus Isoform Prmt2l2: Cytoplasm Predominantly Cytoplasmic
Alternative Antibody Names	Anti-Protein Arginine N-Methyltransferase 2 antibody Anti-Histone-Arginine N-Methyltransferase Prmt2 antibody Anti-PRMT2 antibody Anti-HMT1 antibody Anti-HRMT1L1 antibody

Information sourced from Uniprot.org

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