Anti-PRL1/PTP4A1 antibody (C-Term) (STJ70584)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-PRL1/PTP4A1 (C-Term) is suitable for use in ELISA, Western Blot and Immunofluorescence research applications. |
| Applications | Pep-ELISA/WB/IF |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: This antibody has been successfully used in Western Blot as descibed in the following papers, PMID: 18997816 and PMID: 36793871.IF: Strong expression of the protein seen in HeLa a |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | PTP4A1 |
| Gene ID | 7803 |
| Uniprot ID | TP4A1_HUMAN |
| Accession Number | NP_003454.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | CFKDSNGHRNN |
Additional Info
| Post Translational Modifications | Farnesylated. Farnesylation is required for membrane targeting. Unfarnesylated forms are shifted into the nucleus. |
| Function | Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. |
| Protein Name | Protein Tyrosine Phosphatase Type Iva 1Ptp(CaaxiProtein-Tyrosine Phosphatase 4a1Protein-Tyrosine Phosphatase Of Regenerating Liver 1Prl-1 |
| Cellular Localisation | Cell MembraneLipid-AnchorEarly EndosomeEndoplasmic ReticulumCytoplasmCytoskeletonSpindleNucleusAnd Mitotic Spindle |
| Alternative Antibody Names | Anti-Protein Tyrosine Phosphatase Type Iva 1 antibodyAnti-Ptp(Caaxi antibodyAnti-Protein-Tyrosine Phosphatase 4a1 antibodyAnti-Protein-Tyrosine Phosphatase Of Regenerating Liver 1 antibodyAnti-Prl-1 antibodyAnti-PTP4A1 antibodyAnti-PRL1 antibodyAnti-PTPCAAX1 antibody |
Information sourced from Uniprot.org