Anti-PRKCSH antibody (130-275) (STJ11103549)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PRKCSH (130-275) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PRKCSH |
| Gene ID | 5589 |
| Uniprot ID | GLU2B_HUMAN |
| Immunogen Region | 130-275 |
| Immunogen Sequence | MAEVTREGFRLKKILIEDWK KAREEKQKKLIELQAGKKSL EDQVEMLRTVKEEAEKPERE AKEQHQKLWEEQLAAAKAQQ EQELAADAFKELDDDMDGTV SVTELQTHPELDTDGDGALS EAEAQALLSGDTQTDATSFY DRVWAA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 130-275 of human PRKCSH (P14314). |
Additional Info
| Function | Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia. |
| Protein Name | Glucosidase 2 Subunit Beta80k-H ProteinGlucosidase Ii Subunit BetaProtein Kinase C Substrate 60.1 Kda Protein Heavy ChainPkcsh |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-532668Reactome: R-HSA-879415Reactome: R-HSA-8957275Reactome: R-HSA-901042Reactome: R-HSA-9683686Reactome: R-HSA-9694548 |
| Cellular Localisation | Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Glucosidase 2 Subunit Beta antibodyAnti-80k-H Protein antibodyAnti-Glucosidase Ii Subunit Beta antibodyAnti-Protein Kinase C Substrate 60.1 Kda Protein Heavy Chain antibodyAnti-Pkcsh antibodyAnti-PRKCSH antibodyAnti-G19P1 antibody |
Information sourced from Uniprot.org