Anti-PRKAR2A antibody [Hs-36] (STJ16103387)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgM
ImmunogenFreshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization.
General Information
| Short Description | Mouse monoclonal anti-PRKAR2A for use in ICC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ICC/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | Hs-36 |
| Isotype | IgM |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods). |
| Formulation | Tris buffered saline (TBS) , pH 8.0, 15 mM sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | PRKAR2A |
| Gene ID | 5576 |
| Uniprot ID | KAP2_HUMAN |
| Immunogen | Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization. |
Additional Info
| Post Translational Modifications | Phosphorylated by the activated catalytic chain. |
| Function | Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. |
| Protein Name | Camp-Dependent Protein Kinase Type Ii-Alpha Regulatory Subunit |
| Database Links | Reactome: R-HSA-163615Reactome: R-HSA-164378Reactome: R-HSA-180024Reactome: R-HSA-381676Reactome: R-HSA-432040Reactome: R-HSA-442720Reactome: R-HSA-5610787Reactome: R-HSA-9010642Reactome: R-HSA-9634597Reactome: R-HSA-9660821Reactome: R-HSA-9664323Reactome: R-HSA-983231Reactome: R-HSA-9856530 |
| Cellular Localisation | CytoplasmCell MembraneColocalizes With Pja2 In The Cytoplasm And The Cell Membrane |
| Alternative Antibody Names | Anti-Camp-Dependent Protein Kinase Type Ii-Alpha Regulatory Subunit antibodyAnti-PRKAR2A antibodyAnti-PKR2 antibodyAnti-PRKAR2 antibody |
Information sourced from Uniprot.org