Anti-PREX2 antibody (STJA0008547)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PREX2
General Information
| Short Description | Rabbit polyclonal anti-Phosphatidylinositol 3, 4, 5-trisphosphate-dependent Rac exchanger 2 protein-dependent Rac exchanger 2 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PREX2 |
| Gene ID | 80243 |
| Uniprot ID | PREX2_HUMAN |
| Immunogen | Synthesized peptide derived from human PREX2 |
| Specificity | This antibody detects endogenous levels of PREX2 at Human, Mouse |
Additional Info
| Function | Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase. |
| Protein Name | Phosphatidylinositol 3 -4 -5-Trisphosphate-Dependent Rac Exchanger 2 ProteinP-Rex2Ptdins(3 -4 -5-Dependent Rac Exchanger 2Dep Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-8948751Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Phosphatidylinositol 3 -4 -5-Trisphosphate-Dependent Rac Exchanger 2 Protein antibodyAnti-P-Rex2 antibodyAnti-Ptdins(3 -4 -5-Dependent Rac Exchanger 2 antibodyAnti-Dep Domain-Containing Protein 2 antibodyAnti-PREX2 antibodyAnti-DEPDC2 antibody |
Information sourced from Uniprot.org