Anti-PREX1 antibody (815-836) {Biotin} (STJ502649)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenSynthetic peptide corresponding to aino acid region 815-836 of Human PREX1. Peptide was covalently modified.
General Information
| Short Description | Rabbit polyclonal antibody anti-PREX1 (815-836) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Biotin |
| Concentration | 0.6 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500-1:750DB: 1:20, 000-1:50, 000ELISA: 1:20, 000-1:50, 000IP: 1:200IHC: 1:50-1:150 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | PREX1 |
| Gene ID | 57580 |
| Uniprot ID | PREX1_HUMAN |
| Immunogen | Synthetic peptide corresponding to aino acid region 815-836 of Human PREX1. Peptide was covalently modified. |
| Immunogen Region | 815-836 |
Additional Info
| Tissue Specificity | Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues. |
| Function | Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils. |
| Protein Name | Phosphatidylinositol 3 -4 -5-Trisphosphate-Dependent Rac Exchanger 1 ProteinP-Rex1Ptdins(3 -4 -5-Dependent Rac Exchanger 1 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013406Reactome: R-HSA-9013408Reactome: R-HSA-9013409Reactome: R-HSA-9013423 |
| Cellular Localisation | CytoplasmCytosolCell MembraneMainly CytosolicSome Amount Is Apparently Associated To The Plasma Membrane |
| Alternative Antibody Names | Anti-Phosphatidylinositol 3 -4 -5-Trisphosphate-Dependent Rac Exchanger 1 Protein antibodyAnti-P-Rex1 antibodyAnti-Ptdins(3 -4 -5-Dependent Rac Exchanger 1 antibodyAnti-PREX1 antibodyAnti-KIAA1415 antibody |
Information sourced from Uniprot.org