| Host: |
Rabbit |
| Applications: |
WB/ELISA/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Peroxiredoxin-4 (112-162 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PRDX4 |
| Gene ID: |
10549 |
| Uniprot ID: |
PRDX4_HUMAN |
| Immunogen Region: |
112-162 aa |
| Specificity: |
This antibody detects endogenous levels of PRDX4 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human PRDX4 at the amino acid range 112-162 |
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. |
| Protein Name | Peroxiredoxin-4Antioxidant Enzyme Aoe372Aoe37-2Peroxiredoxin IvPrx-IvThioredoxin Peroxidase Ao372Thioredoxin-Dependent Peroxide Reductase A0372Thioredoxin-Dependent Peroxiredoxin 4 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmEndoplasmic ReticulumCotranslationally Translocated To And Retained Within The Endoplasmic ReticulumA Small Fraction Of The Protein Is Cytoplasmic |
| Alternative Antibody Names | Anti-Peroxiredoxin-4 antibodyAnti-Antioxidant Enzyme Aoe372 antibodyAnti-Aoe37-2 antibodyAnti-Peroxiredoxin Iv antibodyAnti-Prx-Iv antibodyAnti-Thioredoxin Peroxidase Ao372 antibodyAnti-Thioredoxin-Dependent Peroxide Reductase A0372 antibodyAnti-Thioredoxin-Dependent Peroxiredoxin 4 antibodyAnti-PRDX4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
