| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Peroxiredoxin-4 (112-162 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 IHC-P 1:50-300 ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PRDX4 |
| Gene ID: | 10549 |
| Uniprot ID: | PRDX4_HUMAN |
| Immunogen Region: | 112-162 aa |
| Specificity: | This antibody detects endogenous levels of PRDX4 at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human PRDX4 at the amino acid range 112-162 |
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. |
| Protein Name | Peroxiredoxin-4 Antioxidant Enzyme Aoe372 Aoe37-2 Peroxiredoxin Iv Prx-Iv Thioredoxin Peroxidase Ao372 Thioredoxin-Dependent Peroxide Reductase A0372 Thioredoxin-Dependent Peroxiredoxin 4 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Cytoplasm Endoplasmic Reticulum Cotranslationally Translocated To And Retained Within The Endoplasmic Reticulum A Small Fraction Of The Protein Is Cytoplasmic |
| Alternative Antibody Names | Anti-Peroxiredoxin-4 antibody Anti-Antioxidant Enzyme Aoe372 antibody Anti-Aoe37-2 antibody Anti-Peroxiredoxin Iv antibody Anti-Prx-Iv antibody Anti-Thioredoxin Peroxidase Ao372 antibody Anti-Thioredoxin-Dependent Peroxide Reductase A0372 antibody Anti-Thioredoxin-Dependent Peroxiredoxin 4 antibody Anti-PRDX4 antibody |
Information sourced from Uniprot.org