| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPP6R2 |
| Gene ID: | 9701 |
| Uniprot ID: | PP6R2_HUMAN |
| Immunogen Region: | 640-959 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 640-959 of human PPP6R2 (NP_001229827.1). |
| Immunogen Sequence: | EDSDTRCAARVMARPRFGAP HASESCSKNGPERGGQDGKA SLEAHRDAPGAGAPPAPGKK EAPPVEGDSEGAMWTAVFDE PANSTPTAPGVVRDVGSSVW AAGTSAPEEKGWAKFTDFQP FCCSESGPRCSSPVDTECSH AEGSRSQGPEKAFSPASPCA WNVCVTRKAPLLASDSSSSG GSHSEDGDQKAASAMDAVSR GPGREAPPLPTVARTEEAVG RVGCADSRLLSPACPAPKE |
| Tissue Specificity | Ubiquitously expressed with strongest expression in the testis followed by liver, heart, kidney, brain and placenta. |
| Function | Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. |
| Protein Name | Serine/Threonine-Protein Phosphatase 6 Regulatory Subunit 2 Saps Domain Family Member 2 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 6 Regulatory Subunit 2 antibody Anti-Saps Domain Family Member 2 antibody Anti-PPP6R2 antibody Anti-KIAA0685 antibody Anti-PP6R2 antibody Anti-SAPS2 antibody |
Information sourced from Uniprot.org
![Immunoprecipitation analysis of 300 Mu g extracts of U-87 cells using 3 Mu g [KO Validated] ZMYND8 Rabbit polyclonal antibody (STJ11104587). Western blot was performed from the immunoprecipitate using [KO Validated] ZMYND8 Rabbit polyclonal antibody (STJ11104587) at a dilition of 1:1000.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/177231/368825/STJ11104587_1__31783.1713134287.jpg?c=1 "Immunoprecipitation analysis of 300 Mu g extracts of U-87 cells using 3 Mu g [KO Validated] ZMYND8 Rabbit polyclonal antibody (STJ11104587). Western blot was performed from the immunoprecipitate using [KO Validated] ZMYND8 Rabbit polyclonal antibody (STJ11104587) at a dilition of 1:1000.")
