Anti-PPP1R14B antibody (68-147) (STJ116879)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PPP1R14B (68-147) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPP1R14B |
| Gene ID | 26472 |
| Uniprot ID | PP14B_HUMAN |
| Immunogen Region | 68-147 |
| Immunogen Sequence | RLNLEEWILEQLTRLYDCQE EEIPELEIDVDELLDMESDD ARAARVKELLVDCYKPTEAF ISGLLDKIRGMQKLSTPQKK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 68-147 of human PPP1R14B (NP_619634.1). |
Additional Info
| Tissue Specificity | Ubiquitous. Expressed at low levels. |
| Post Translational Modifications | Phosphorylated primarily on Thr-57 by PKC (in vitro). An unknown Ser is also phosphorylated by PKC (in vitro). |
| Function | Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 14bPhospholipase C-Beta-3 Neighbouring Gene Protein |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Protein Phosphatase 1 Regulatory Subunit 14b antibodyAnti-Phospholipase C-Beta-3 Neighbouring Gene Protein antibodyAnti-PPP1R14B antibodyAnti-PLCB3N antibodyAnti-PNG antibody |
Information sourced from Uniprot.org