| Short Description : | Rabbit polyclonal anti-Apoptosis-stimulating of p53 protein 1 (630-680 aa) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | IHC-P 1:50-200ELISA 1:10000-20000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPP1R13B |
| Gene ID: | 23368 |
| Uniprot ID: | ASPP1_HUMAN |
| Immunogen: | Synthetic peptide from the human protein at the amino acid range 630-680 |
| Immunogen Region: | 630-680 aa |
| Specificity: | The antibody detects endogenous ASPP1 |
| Function | Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. |
| Protein Name | Apoptosis-Stimulating Of P53 Protein 1Protein Phosphatase 1 Regulatory Subunit 13b |
| Database Links | Reactome: R-HSA-139915Reactome: R-HSA-6803204Reactome: R-HSA-6803205Reactome: R-HSA-6803211Reactome: R-HSA-6804759 |
| Cellular Localisation | CytoplasmNucleusPredominantly CytoplasmicSome Fraction Is Nuclear |
| Alternative Antibody Names | Anti-Apoptosis-Stimulating Of P53 Protein 1 antibodyAnti-Protein Phosphatase 1 Regulatory Subunit 13b antibodyAnti-PPP1R13B antibodyAnti-ASPP1 antibodyAnti-KIAA0771 antibody |
Information sourced from Uniprot.org
