Anti-PPP1R12B antibody (STJA0007634)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PPP1R12B
General Information
| Short Description | Rabbit polyclonal anti-Protein phosphatase 1 regulatory subunit 12B for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPP1R12B |
| Gene ID | 4660 |
| Uniprot ID | MYPT2_HUMAN |
| Immunogen | Synthesized peptide derived from human PPP1R12B |
| Specificity | This antibody detects endogenous levels of PPP1R12B at Human |
Additional Info
| Function | Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 12bMyosin Phosphatase-Targeting Subunit 2Myosin Phosphatase Target Subunit 2 |
| Database Links | Reactome: R-HSA-2565942 O60237-4Reactome: R-HSA-5625740Reactome: R-HSA-5625900Reactome: R-HSA-5627117Reactome: R-HSA-5627123 |
| Cellular Localisation | CytoplasmCytoskeletonStress FiberAlong Actomyosin Filaments |
| Alternative Antibody Names | Anti-Protein Phosphatase 1 Regulatory Subunit 12b antibodyAnti-Myosin Phosphatase-Targeting Subunit 2 antibodyAnti-Myosin Phosphatase Target Subunit 2 antibodyAnti-PPP1R12B antibodyAnti-MYPT2 antibody |
Information sourced from Uniprot.org