• Western blot analysis of various lysates using PPP1R12B Rabbit polyclonal antibody (STJ119602) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-PPP1R12B antibody (660-930) (STJ119602)

SKU:
STJ119602

$151.88 - $705.38
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PPP1R12B (660-930) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PPP1R12B
Gene ID: 4660
Uniprot ID: MYPT2_HUMAN
Immunogen Region: 660-930
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 660-930 of human PPP1R12B (NP_002472.2).
Immunogen Sequence: TFSRSRAERQAQEQPREKPT DTEGLEGSPEKHEPSAVPAT EAGEGQQPWGRSLDEEPICH RLRCPAQPDKPTTPASPSTS RPSLYTSSHLLWTNRFSVPD SESSETTTNTTTAKEMDKNE NEEADLDEQSSKRLSIRERR RPKERRRGTGINFWTKDEDE TDGSEEVKETWHERLSRLES GGSNPTTSDSYGDRASARAR REAREARLATLTSRVEEDSN RDYKKLYESALTENQKLKT
Tissue Specificity Detected in skeletal muscle, fetal and adult heart, brain, placenta, kidney, spleen, thymus, pancreas and lung. Isoform 3 and isoform 4 are heart specific.
Function Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus.
Protein Name Protein Phosphatase 1 Regulatory Subunit 12b
Myosin Phosphatase-Targeting Subunit 2
Myosin Phosphatase Target Subunit 2
Database Links Reactome: R-HSA-2565942 O60237-4
Reactome: R-HSA-5625740
Reactome: R-HSA-5625900
Reactome: R-HSA-5627117
Reactome: R-HSA-5627123
Cellular Localisation Cytoplasm
Cytoskeleton
Stress Fiber
Along Actomyosin Filaments
Alternative Antibody Names Anti-Protein Phosphatase 1 Regulatory Subunit 12b antibody
Anti-Myosin Phosphatase-Targeting Subunit 2 antibody
Anti-Myosin Phosphatase Target Subunit 2 antibody
Anti-PPP1R12B antibody
Anti-MYPT2 antibody

Information sourced from Uniprot.org

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