Host: |
Rabbit |
Applications: |
IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-E3 ubiquitin-protein ligase PPP1R11 (71-120 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PPP1R11 |
Gene ID: |
6992 |
Uniprot ID: |
PP1RB_HUMAN |
Immunogen Region: |
71-120 aa |
Specificity: |
Tctex5 Polyclonal Antibody detects endogenous levels of Tctex5 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human PPP1R11 at the amino acid range 71-120 |
Post Translational Modifications | Auto-ubiquitinated. |
Function | Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1. |
Protein Name | E3 Ubiquitin-Protein Ligase Ppp1r11Hemochromatosis Candidate Gene V ProteinHcg VProtein Phosphatase 1 Regulatory Subunit 11Protein Phosphatase Inhibitor 3 |
Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Ppp1r11 antibodyAnti-Hemochromatosis Candidate Gene V Protein antibodyAnti-Hcg V antibodyAnti-Protein Phosphatase 1 Regulatory Subunit 11 antibodyAnti-Protein Phosphatase Inhibitor 3 antibodyAnti-PPP1R11 antibodyAnti-HCGV antibodyAnti-TCTE5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance