Anti-PPP1R11 antibody (71-120 aa) (STJ95954)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PPP1R11 at the amino acid range 71-120
General Information
| Short Description | Rabbit polyclonal anti-E3 ubiquitin-protein ligase PPP1R11 (71-120 aa) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPP1R11 |
| Gene ID | 6992 |
| Uniprot ID | PP1RB_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PPP1R11 at the amino acid range 71-120 |
| Immunogen Region | 71-120 aa |
| Specificity | Tctex5 Polyclonal Antibody detects endogenous levels of Tctex5 protein. |
Additional Info
| Post Translational Modifications | Auto-ubiquitinated. |
| Function | Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1. |
| Protein Name | E3 Ubiquitin-Protein Ligase Ppp1r11Hemochromatosis Candidate Gene V ProteinHcg VProtein Phosphatase 1 Regulatory Subunit 11Protein Phosphatase Inhibitor 3 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Ppp1r11 antibodyAnti-Hemochromatosis Candidate Gene V Protein antibodyAnti-Hcg V antibodyAnti-Protein Phosphatase 1 Regulatory Subunit 11 antibodyAnti-Protein Phosphatase Inhibitor 3 antibodyAnti-PPP1R11 antibodyAnti-HCGV antibodyAnti-TCTE5 antibody |
Information sourced from Uniprot.org