Anti-PPM1E antibody [R54-6U-5] (STJA0035567)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human PPM1E
General Information
| Short Description | Rabbit monoclonal anti-PPM1E for use in WB and FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/FC |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R54-6U-5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000FC 1:50 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PPM1E |
| Gene ID | 22843 |
| Uniprot ID | PPM1E_HUMAN |
| Immunogen | A synthesized peptide derived from human PPM1E |
Additional Info
| Function | Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2. |
| Protein Name | Protein Phosphatase 1eCa(2+/Calmodulin-Dependent Protein Kinase Phosphatase NCamkp-NCamkp-NucleusCamknPartner Of Pix 1Partner Of Pix-AlphaPartner Of Pixa |
| Database Links | Reactome: R-HSA-9617324 |
| Cellular Localisation | NucleusCytoplasmA Truncated FormMajor FormWith The C-Terminal Part MissingIs Mostly Found In The Cytoplasm And A Little In The NucleusThe Full-LengthMinor FormIs Found In The Nucleus |
| Alternative Antibody Names | Anti-Protein Phosphatase 1e antibodyAnti-Ca(2+/Calmodulin-Dependent Protein Kinase Phosphatase N antibodyAnti-Camkp-N antibodyAnti-Camkp-Nucleus antibodyAnti-Camkn antibodyAnti-Partner Of Pix 1 antibodyAnti-Partner Of Pix-Alpha antibodyAnti-Partner Of Pixa antibodyAnti-PPM1E antibodyAnti-CAMKN antibodyAnti-KIAA1072 antibodyAnti-POPX1 antibody |
Information sourced from Uniprot.org